Dexamethasone modulation ofMUC5ACandMUC2gene expression in a generalized model of middle ear inflammation
نویسندگان
چکیده
منابع مشابه
Dexamethasone modulation of MUC5AC and MUC2 gene expression in a generalized model of middle ear inflammation.
OBJECTIVES/HYPOTHESIS To examine the effect of dexamethasone on basal and proinflammatory cytokine-induced gel-forming mucin expression in human middle ear epithelial cell line (HMEEC-1). METHODS HMEEC-1 was exposed to proinflammatory cytokines, tumor necrosis factor-alpha (TNF-), and interleukin-1 beta (IL-1β) to identify optimal mucin induction. The HMEEC-1 was incubated with dexamethasone ...
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ژورنال
عنوان ژورنال: The Laryngoscope
سال: 2015
ISSN: 0023-852X
DOI: 10.1002/lary.25762